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Precision treatment using Multi-modal Monitoring helps save children’s lives from Septic shock: Apollo Children’s Hospitals

Chennai ,May 2017: What might look as an ordinary fever can turn fatal over hours and it can occur due to a complication known as sepsis that escalates, beginning with a flu, pneumonia or urinary tract infection. Severe sepsisis a leading cause death in many young children around the world. Apollo Children’s Hospitals has identified this serious condition and has succeeded in providing precision medicine to an 8year old child who was battling for her life after developing a septic shock due to a rapidly progressive pneumonia.

The child developed symptoms of high fever and breathlessness and slipped into septic shock leading to low blood pressure and oxygen levels. “She developed multiple organ failure where her lungs, liver and kidney started to lose its function one by one.The referring hospital administered the standard Septic Shock protocol, despite which she continued to rapidly deteriorate. She was referred to Apollo Children’s Hospital PICU for possible rescue extracorporeal life support, a technologically advanced therapy.

On arrival, the PICU team assessed each aspect of her circulation using multimodal monitoring, with particular focus on herfluid status, cardiac output, blood vessel tone and lung condition. This permitted precise fine-tuning of therapy includingfluids, cardiac medications and vascular support thus preventing under treatment or over-treatment, both which may result in worse multi-organ failure and death.

The mortality rate due to septic shock is between 20-50% in India, and this may vary according to the expertise involved in treatments.” said, Dr Suchitra Ranjit, Senior Consultant, PaediatricIntensive Care, Apollo Hospitals on describing the case. At Apollo Children’s Hospital, where the leading edge precision therapy using multimodal therapy was performed, septic shock mortality is 8-9%.

The information obtained by multimodal monitoring resulted in a complete change in the cardiac support treatment regimen, such that within a few hours, her circulation blood pressure and blood flow to vital organs improved dramatically.There was no requirement for extracorporeal life-support. Within hours her urine flow and kidney function improved, and in 3days, she was offthe ventilator.

Sepsis is a life threatening condition that can affect both young and old individuals; especially the newborns and children below the age of 10 who are more vulnerable owing to their weak immune systems. “This condition is unfamiliar to the general publicthough it poses a risk to one’s life. Apollo, which has always been in the upfront for providing best quality treatment and care, has also been keen on continuous research and developmentin the field of medicine. Ourteam of experts ensures they are updated with the latest technological advancements and findings in treatment methods. We carry the spirit to explore new areas in the field of medicine and our case studies stand as a testimony to our work.Apollo is proud to say that Dr. Suchitra Ranjitis the only Indian lead author in the recent International Septic Shock Guideline by virtue of her research on multimodal monitoring and precision therapy,” said Ms. Preetha Reddy, Executive Vice Chair Person, Apollo Hospitals.

About Apollo Hospitals group:

It was in 1983, that Dr.Prathap Reddy made a pioneering endeavour bylaunching India’s first corporate hospital – Apollo Hospitals in Chennai. Over the years ApolloHospitals has established itself as home to the largest cardiac practice in India with over 160,000cardiac surgeries. Apollo Hospitals is also the world’s largest private cancer care provider and runsthe world’s leading solid organ transplant program.Now, as Asia’s largest and most trusted healthcare group, its presence includes 8,488 beds across 51 Hospitals, 1,586 Pharmacies, 92 Primary Care and Diagnostic Clinics, 100 Telemedicine units across10 countries. Health Insurance services, Global Projects Consultancy, 15 colleges of Nursing andHospital Management and a Research Foundation with a focus on global Clinical Trials,epidemiological studies, stem cell & genetic research and the first Proton Therapy Center acrossAsia, Africa and Australia.In a rare honor, the Government of India issued a commemorative stamp in recognition of Apollo’scontribution, the first for a healthcare organization. Apollo Hospitals Chairman, Dr.Prathap C Reddy,was conferred with the prestigious Padma Vibhushan in 2010. For more than 28 years, the ApolloHospitals Group has continuously excelled and maintained leadership in medical innovation, world-class clinical services and cutting-edge technology. Our hospitals are consistently rankedamongst the best hospitals globally for advanced medical services and research.

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